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ASTS - 2013 American Transplant Congress - Nurses ONLY
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Agreement
By completing this form, you attest that you have participated in all selected activities in thier entirety.
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
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Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
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Please rate the speaker(s) as a group.  You will have the opportunity to elaborate on an individual speaker in the following question. 
Please rate the following:
The program was relevant to my work.
Content matched stated objectives.
Usefulness of handouts/AV.
Quality of facilities.
How well did the educational sessions give a balanced view of therapeutic options, including the use of generic names?
If you rated any of the above questions with 'fair,' 'poor,' 'disagree,' or 'strongly disagree' please explain in detail (e.g. session title, speaker name, situtation):
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If you have additional comments regarding the session or individual speaker(s) - e.g. teaching ability, expertise, organization of materials, etc. - please use the space below:
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Having completed the activity, please rate your ability to meet each of the following objectives:
Discuss the role of Tregs in transplantation
List the major subsets of Thelper cells
Identify key intracellular signaling pathways in T lymphocytes
Discuss positive and negative pathways
Discuss the sources of DAMPS
Review humoral immune response in the context of transplantion
Review the risk factors for PTLD
Examine the risk factors, pathogensis, and pathologic heterogeneity of post-transplant lymphoproliferative disorders
Discuss standard therapy and new/novel therapeutic options for patients with post-transplant lymphoproliferative disorders
Discuss current approaches to examining the immune and viral factors contributing to PTLD
Discuss the impact of genetic risk variants in kidney donors on allograft survival
Examine APOL1 gene variations among African American kidney transplant recipients
Explore the impact of APOL1 gene variants on transplant outcomes
Discuss the existence racial disparities in kidney disease risk
Define the role of variants in the APOL1 gene in explaining this disparity
Define role of cultural compentency and congruency in kidney transplantation for Hispanic Americans
Discuss advantages and disadvantages of a transplant centered approach to address kidney transplant disparities in Hispanic Americans
Discuss the power of grass roots and media interactions to change community mindsets
Facilitate cross-generational, public support for organ and tissue donation
Discuss current challenges with conventional calcineurin inhibitor-based transplant immunosuppression regimens
Define the role and importance of PD1/PDL1 coinhitibition on the alloimmune response
Discuss role of belatacept and anti-CD40 in inhibiting costimulation
Explain the principles of costimulatory blockade
List novel strategies for CMV prevention
Define the role of chromatin in controlling gene expression
Evaluate risk factors of CMV disease after transplantation
Discuss antibody vs non-antibody mediated functions of B cells
Name and discuss at least three mechanisms by which B cells may contribute to allograft rejection process
Explain the concept of B cell regulation and give several examples of this phenomenon in transplant settings
Describe the CMS requirements for transplant pharmacists in the phases of transplant
Differentiate between methods for billing transplant pharmacy services
List five actionable methods for increasing revenue or cost saving strategies that can be used to justify and support transplant pharmacy services
List the fundamental and desirable activities of the transplant pharmacist on the multidisciplinary transplant team
Articulate the requirements for informed consent for potential living donors
Identify how to incorporate the independent donor advocate into the donation process
Identify areas for living donor process improvement from referral to donation
Review and evaluate the latest clinical science advances in living donor education
Present cases of high risk donors
Discuss the main molecular processes of autophagy
Demonstrate a cytoprotective role of autophagy in kidney injury
Define the diverse role of autophagy proteins
Recognize the effect on immunosuppression on autophagy
Describe the risk factors associated with development of anti-HLA antibodies
Review state-of-the-art metabolomic technologies
Discuss hurdles to implement metabolomic technologies into clinical practice
Outline the classic pathology related to antibody-mediated rejection
Discuss approaches to enhance recognition and diagnosis of late AMR
Discuss the indication for transpant in morbidly obese patients
Define the role of superficial wound infection in the outcome of kidney transplantaton
Discuss the evolution of combined use of natural orifice and laparoscopic surgery for kidney transplantation
Discuss technical development/present procedures regarding MIS Kidney Transplantation (MIKT), in particular open MIKT
Identify potential tasks in transplantation well suited to Mobile Phone Apps
List characteristics of useful mobile apps
Explain how a web application can be used in the initial screening of living kidney donors
Utlize wireless enabled electronic pill bottles to improve adherence among transplant recipients
Discuss the impact of donor-specific antibody on liver allograft function
Explain how class I and II DSA are different
Define the risk of rejeciton in liver transplant patients with preformed class II DSA
Describe the use of Solid Phase assays for evaluation of HLA antibodies
Define the role of Donor Specific HLA Antibodies in Solid Organ Transplantation
Discuss the pathophysiology of sensitization and antibody mediated-rejection
Identify patients at risk for sensitization and determine their extent of sensitization
Review the prevalence of allosensitization
Discuss different assays to detect circulating antibodies and explain how these tests should be ordered and interpreted
Review and evaluate the latest clinical and basic science advances in transplantation science, medicine and surgery
Discuss important immunologic mechanisms of rejection in lung transplantation
Define the role of genomics in predicting outcomes after lung transplant
Discuss lung transplantation as a bridge to transplant mechanical support
Discuss challenging cases of graft pathology
Explain why interpretation of biopsy findings may require careful clinicopathological correlations
Discuss the clinical implication of identifying focal segmental glomerulosclerosis in early and late post-transplant kidney allograft biopsies
Discuss the clinical implication of identifying "transplant glomerulopathy" in patients with no evidence of DSA
Describe the consequences of CTLA4-Ig treatment on Tregs
Discuss the possibility of increased acute rejection after CTLA4-Ig
Explain how CTLA-4Ig is used in combination with other agents as part of a maintenance immunosuppressive regimen
List the differences in transplant outcomes associated with CTLA-4Ig-based immunosuppressive regimens and conventional regimens
Explain what is meant by the concept "quality of life”
List the most important risk factors for mental health problems and quality of life decrements after organ transplantation
Review cognitive behavioral coping skills that can be helpful in reducing stress, improving psychological adjustment, and improving quality of life among caregivers
Describe common strategies to optimizing ambulatory transplant care
Describe the CMS and UNOS requirements for transplant pharmacists throughout the continuum of care
Discuss outcomes of VAD therapy on pre and post transplant survival
Review the applicable UNOS data and recent peer-reviewed publications relevant to altering the cardiac allograft allocation scheme
Discuss the impact of change in heart allocation on; wait list mortalitym, ischemic time and post-transplant outcomes
Discuss the Eurotransplant heart allocation policy
Discuss the injury associated with ischemia reperfusion and delayed graft function in organ transplantation
Discuss the outcomes of Phase 1 and 2 trials in the use of Diannexin for recipients of deceased donor kidneys at a high risk for delayed graft function
Discuss the status of research surrounding prophlaxis and treatment of DGF
Discuss the impact of delayed graft function on graft survival and current strategies to decrease the rate of delayed graft function
Discuss the mechanism of action of I5-NP and clinical trials in kidney transplant recipients
Discuss the latest data on virological response with use of DDA for HCV post-liver transplantation
Describe the challenges of using DDA post-liver transplant
Discuss the natural history of HCV after liver transplantation
Explain the side effects of HCV treatments after liver transplantation
Recognize the need for properly designed research protocols in deceased donor intervention trials
Recognize the need for properly designed research protocols in deceased donors
Discuss the major barriers to the design and conduct of donor intervention protocols
Discuss the basics of the IND process and to list resources where additional information on IND applications can be found
Discuss the responsibilities of a clinical investigator including the basics of good clinical practice (GCP) and the 1572 form
Explain the basics of a FDA audit
Discuss potential methods to increase the number of referrals to your center
Discuss methods of building a living donor kidney and/or liver program to balance the needs of patients while appreciating the organ shortage
Identify components necessary for programmatic growth
List the pitfalls that accompany programmatic growth
Discuss the diagnosis of multi-drug resistant organisms in solid organ transplant recipients
Describe the treatment of multi-drug resistant organisms in solid organ transplant recipients
Identify components necessary for programmatic growth
Discuss the pathology of renal allograft rejection
Discuss subclinical pathology in renal allografts
Discuss the utility of multiplex bead assays for HLA antibody
Identify the limitations on interpretation of antibody assays
Define the role of IL-2 in conventional T cell homeostasis, differentiation and function
Discuss the complex roles of IL-2 in tolerance and immunity
Differentiate the impact of IL-2 neutralisation on T cell subsets - effector T cells vs Treg
Discuss the potential clinical implications of IL-2 neutralisation on T cell function
Review the epidemiology of bacterial, fungal, viral infections after lung transplantation
Discuss the optimal duration of CMV prophylaxis in the lung transplant population
Discuss the impact of pre-lung transplant donor and recipient pulmonary colonization with bacterial pathogens
Define "elevated infectious disease transmission"
Explain what UNOS/OPTN requirements are for consent
Cite the risks of disease transmission from donors to recipients
Explain comparative risk assessment
Explain what constitutes reasonable expectations from allograft biopsies
Discuss the traditional and emerging roles of C4d in allograft biopsies as well as its shortcomings
Discuss specific histological features in allograft biopsies
Review risk factors and pathogenesis of NODAT, describing recent pre-transplant risk models for NODAT
Discuss if resting the pancreas with insulin therapy immediately after transplant can prevent NODAT
Manage new onset diabetes after transplantation
Discuss noval approaches in preventing new onset diabetes after transplantation
Describe how NK cells promote allograft rejection
Explain how NK cells faciliate tolerance induction
Discuss how NK cells bridge the gap between innate and adaptive immunity
Characterize the benefit and risk of utilizing marginal donor livers for transplantation
Identify donor and recipient risk factors that contribute to poor outcome when using marginal deceased donor livers
Identify the benefits and risks of using marginal donor livers based on recipient severity of disease and MELD score
Explore the opportunities for role development in Advanced Practice
Explore educational resources
Discuss mentoring opportunities for advanced practice
Discuss how the HLA laboratory tests for HLA antibodies
Utilize of the virtual crossmatch in heart transplant
Define role of the HLA laboratory in diagnosis and treatment of AMR in heart transplantation
Define the role of alarmins in tissue damage due to ischemia/reperfusion
Discuss the role of alarmins in innate - adaptive host immune responses in transplant recipients
Discuss the potential antitumor effects of alarmins
Define how IL-33 interacts with other cytokines and pro-inflammatory stimuli to induce Th1, Th2 and regulatory immune response
Discuss the potential ways that IL-33 related pathways may be targeted to improve transplant outcomes
Discuss the incidence and identify the risk factors for hyperlipidemia following kidney transplantation
Describe the risk of skin cancer in transplant patients
Review the relevant vascular nomenclature, anatomy and its variants relevant for laparoscopic renal donation
Discuss the prevalence of obesity after kidney transplantation
List the most commonly used antihypertensive medications after kidney transplantation
List risk factors associated with medication errors in transplant recipients
Define the role of compatible pairs in KPD program
Identify the challenges to paired kidney donation
Discuss kidney paired donation strategies to transplant patients who have incompatible, but healthy and willing potential donors
List barriers that currently prevent full participation in kidney paired donation (KPD) in the United States and evaluate models to overcome these barriers
Discuss the pro's and con's of digital pathology
Discuss the current state of progress made by the CTOT core labs in standardizing our methods
Discuss the methods to and the impact of standardardization of Flow Cytometry techniques for Transplant Immune Monitoring
Discuss methods to reduce variance in testing and normalization of solid phase HLA antibody test results
Discuss the current portfolio of multi-center clinical trials exploring the safety and efficacy as well as the potential risks and benefits of immunosuppression withdrawal in adult and pediatric liver transplant recipients
Consider unmet needs and priorities for future developments in immunosuppression
Discuss the currently available data in molecular markers in operationally tolerant patients
Recognize the potential advantages of Organ Care System
Discuss the significant impact of hormonal therapy on donor management and organ procurement
Identify candidate strategies to increase safe utilization of "marginal donors"
Explain the genetic theory of infectious diseases
List the known genetic etiologies of pediatric tuberculosis, herpes simplex encephalitis, and invasive pneumococcal diseases
Cite the definition of DAMPS and pattern recognition receptors
Discuss signalling pathways to induce sterile inflammation
Review the relevant literature related to Toll-like 9 receptor (TLR9)
Describe the new kidney allocation policy
Quantify the number of life years that can potentially be obtained from the exisitng deceased donor pool
Propose an alternative kidney allocation model that incorporates age equitably
Discuss career options in transplant research and how interacting with great colleagues worldwide in transplantation enriches ones life
Define the role of a Transplant Pharmacist and the issues that they face in caring for transplant recipients
Identify areas for living donor process improvement from referral to donation
Consider the unique opportunities for clinical and basic research available to transplant surgeons
Discuss the role of the pharmacist in a transplant patient's transition from inpatient to outpatient care
Identify funding strategies for research
Discuss the basis for T cell recognition of lipids as antigens presented by CD1d
Define the role of innate immune cells in allograft responses
Discuss the application of NK cells in the clinic
Discuss NK cell memory
Identify potential genetic polymorphisms of interest based on immunosuppressive drug metabolism
Discuss the risk factors, clinical presentation and clinical significance of the novo Donor specific Antibodies
Identify gene signatures predictive of allograft rejection
Debate the use of incentives in transplantation – etchical vs. necessary
Describe the use of incentives in other health contexts
Discuss the most important ethical issues (undue inducement, unjust inducement and crowding out) related to incentives for organ donation
Discuss the prevalence and impact of medication non adherence in children and adolescents after liver transplantation
Discuss the science & health literacy status of the typical patient
Analyze health literacy interventions to improve transplant patient outcomes
Discuss retrieval and preservation techniques in DCD liver donation/transplantation
Identify and remedy the barriers (e.g. pathophysiologic, clinical, and regulatory) to utilization of livers donated after cardiac death
Discuss how to improve short and long term results after use of DCD donors for liver transplant
Explain how is self-tolerance in T cells "encoded"
Discuss the molecular basis for CD8 T cell deletion
Define the role of inflammatory cytokines in activating virus-specific T cells
Discuss the approaches that are available to monitor the transplanted pancreas
Discuss the relative pros and cons of heterotopic versus orthotopic kidney transplantation for re-operative cases
Explain how to recognize and treat graft injury due to bladder disfunction
Evaluate the positive and negative effects of SRTR regulation
Discuss metrics of geographic disparity in access to transplant
Describe proposed changes in the kidney and liver allocation policies
Discuss areas the SRTR is exploring for future enhancements to the methodologies
Discuss how the total artificial heart works
Recognize right heart failure after implant
Discuss Mechanical Circulatory Support trial results vs. Heart Transplant results
Identify the factors that contribute to decision-making in the context of high-risk solid organ transplantation
Discuss when and how to incorporate discussions around end-of-life in the setting of end-stage organ failure and assessment for organ tranplantation
Discuss the clinical significance of non-HLA antibodies
Discuss approaches for CNI and Steroid minimization
Cite patient and graft benefits of CNI & Steroid minimization
Discuss the genomic technologies to mine for biomarkers
Discuss the need for functional biomarkers for clinical transplant tolerance
Explain the concept of clinical transplantation tolerance
Evaluate current donor criteria for lung transplantation
Define the role of mechanical support in right ventricular failure
Discuss the role of HLA antibodies in lung transplant rejection
Discuss whether women of childbearing age with organ transplants can be ethically excluded from certain medications or clinical trials due to teratogenicity concerns
Identify optimal contraceptive methods in women post-transplant
Identify the emerging health care needs of adolescent solid organ transplant recipients, specifically with regard to 1) developmental needs for privacy 2) pubertal changes 3) contraception
Define the role of Itga4 in T cell trafficking
Discuss intravital tools to address the rules of homing
Discuss sterile inflammation, innate immunity and leukocyte recruitment
Identify the minimal evaluation needed to assess renal function in potential liver transplant recipients
Discuss decision-making for SLK vs. LTA based on long term outcomes
List the most common and serious causes of acute kidney injury in patients with decompensated cirrhosis
Examine the role of social media in increasing organ donation registration
Examine the barriers to increasing organ donor registration
Describe how Facebook has helped promote organ donation and how social medica in general can promote organ donation
Discuss the overall state of donor registration in the United States and the efforts to increase donor designation
Discuss the goals of allocation in general and LAS in particular
Discuss ways of expanding the donor pool such as DCDD donation and ex vivo lung support
Define the role of EVLP in increasing organ supply
Compare the differences in outcomes based on the immunosuppression used at conception and during pregnancy
Describe the role of the National Transplantation Pregnancy Registry (NTPR) and family planning
Review the pregnancy categories of current immunosuppressive therapies with a focus on clinical recommendations for these agents utilized in solid organ transplant recipients
Discuss the impact of health literacy on Hispanic patient receptivity to transplant education
Discuss importance of education about LKT to minority audiences
Explore application of the Information-Motivation-Behavioral Skills (IMB) Model for addressing knowledge of opportunities for and the process, benefits, and risks of living donation
Describe the epidemiology, clinical presentation, diagnosis and potential treatment options for viral respiratory infections in lung transplant recipients
Discuss context of vaccine-preventable illness in pediatric transplant recipients
Review available evidence regarding the role of BK and MC polyomaviruses in tumor development
List the most common causes of diarrhea after transplantation
Identify risk factors for developing PTLD
Discuss management of asymptomatic bacteriuria and sympromatic urinary tract infections in renal transplant recipients
Discuss strategies for prevention of healthcare-associated infections in the solid organ transplant recipient
Discuss transcriptional regulation of T cell immunity
List the pathways through which C3a and C5a alter regulatory cell function and stability in transplantation
Describe how CD28 is important for regulatory T cells
Discuss methods to overcome barriers associated with identifying a living kidney donor
Discuss how kidney paired donation (KPD) has expanded living kidney donation more than any other strategy over the last decade
Review new and developing strategies for increasing and enhancing living kidney donation through KPD
Discuss clinical implications and next steps in evaluation and dissemination of the House Calls intervention
Compare the effectiveness of Explore Transplant(ET) versus standard-of-care transplant education in dialysis centers on increasing patients' informed decision-making and pursuit of transplantintervention
Discuss multilevel medication adherence interventions in solid organ transplantation
Describe how adherence enhancing interventions can help with high risk patients
Discuss medication adherence interventions for their own clinical context
Review recent changes that impact the recruitment and education of transplant professions
Discuss potential strategies to optimize education in the current environment
Describe how to increase resident/fellow interest in the transplant field
Discuss a multidisciplinary curriculum for all transplant trainees
Review the top 10 papers in transplant ID
Identify barriers to the kidney transplant work-up process
Identify core elements of the kidney transplant work-up process and determine which are integral to post-transplant outcomes
Describe their current process for kidney transplant candidate and donor evaluations
Identify areas for improvement within the kidney transplant candidate or donor evaluation process
Discuss the progress of the living donor liver transplantation
Explain why LDLT, especially in adults is more challenging than DDLT
Identify problems with the conventional diagnosis of ABMR
Describe the long-term impact of subclinical ABMR in kidney transplantation
Identify treatment options and outcomes
Discuss the differenct ABMR phenotypes
Discuss the antimycobacterial agents used in standard therapy of latent or active tuberculosis including new treatments that could be used before transplantation
Review the epidemiology and clinical spectrum of tuberculosis in solid organ tranplant patients
Discuss differences in positive test results depending on the type and intensity of immunodeficiency
Discuss the concept of ex vivo normothermic organ preservation and repair
Discuss the current state of the art in lung preservation for transplantation
List the concepts of a personalized medicine approach to the donor organ
Review the risks and benefits of current antiviral therapy peri- transplant
Delineate key management issues with the use of peginterferon/ribavirin with or without telaprevir or boceprevir prior to transplantation
Discuss the natural history of hepatitis C in liver transplantation
Discuss emerging HCV therapies
Review the major factors that increase the risk of infections in the pediatric transplant recipient
Discuss the immunosuppressive agents currently available for transplantation
Discuss aspects of the immature immune system
Discuss potential immune advantages of the young transplant patient
Discuss the evolution of the management of highly sensitized patients
Discuss the immunological concepts involved in the design of desensitization protocols, and patient selection
Describe the short and long-term outcomes of desensitization protocols
Describe aspects of clinical trials
List the most common reasons given for discarding deceased donor kidneys in the United States
Describe the perils and pitfalls of the use of kidney biopsies in deciding whether or not to transplant a kidney
Discuss the principals and the rationale of the Eurotransplant Senior Program (ESP) for kidney allocation and transplantation
Discuss underlying causes of the nearly 20% kidney discard rate that has been observed the past 5+ years
Identify the HIV medications that are most problematic with regards to drug interactions with immunosuppressants
Given a patient case, be able to understand the pharmacokinetic interactions between the ARVâ??s/PI's and immunosuppressants and be able to make the necessary dosage adjustments
Discuss the contribution of single-nucleotide polymorphisms (SNPs) in the CYP3A5 gene to the overall between-patient variability in the pharmacokinetics of tacrolimus
Discuss the effect that telaprevir and boceprevir on PK of the commonly used immunosuppressants
List key areas of progress in understanding mechanisms of allograft injury and acceptance
Review new discoveries in liver, kidney and pancreas transplantations
Discuss potential future directions of basic science efforts in transplantation
Define the role of immunologic memory and its potential impact on allograft outcomes
Identify events in transplantation that stimulate complement activation
Discuss effector cells of cell mediated rejection
Discuss the distinction between innate and adaptive components of the immune response to an allograft
Identify the early immunological events that initiate the rejection response
Discuss the mechanisms of tolerance and how this impacts the development of assays to monitor the immune response following transplantation
Discuss about various types of regulatory cells: Tregs (induced; natural; Tr1) and Bregs 2)
Discuss the impact of temperature and preservation technique on organ quality
Discuss the importance of T cell responses in dictating allograft rejection versus tolerance
Review technical aspect of reopertaive surgery in the trasplant recipients
Discuss preoperative risk identification
Discuss reconstruction options and surgical technique
Discuss the risk factor for cardiac events after kidney transplantation
Describe the purpose(s) of the pre-transplant cardiovascular risk assessment
Describe the feasibility of a randomized trial for pretransplant screening for cardiovascular disease
Discuss physical inactivity as a risk factor for cardiovascular disease
Review current experimental data in heart and lung transplantation tolerance
Discuss the influence of innate immune activation on tolerance induction
Describe the mechanism of action of maintenance immunosuppressive medications
Identify biomarker tests for prediction and diagnosis of heart allograft rejection
Discuss new concepts in immune regulation and the importance of anatomy in tolerance
Discuss the history, results and long-term outcomes of living donor transplantation
List strategies to increase success of clinical research studies in transplant patients
Identify the expectation of suitable heart and lung donors to promote successful transplantation
Cite mitigation strategies for preventing post-transplant infections
Discuss the challenges of expanding kidney transplantation and to place HLA and ABO antibodies into the context of these challenges
Discuss the side effects of immunosuppressive agents that cause toxicity and compromise long-term outcomes
Discuss what type of contributors will be necessary for the future development of transplantation
List the challenges for the adolescent transplant recipient in transferring to adult care and strategies to overcome them
Identify resources and tools that can be used in your center to help adolescents make a smooth transtion to adult care
Discuss adolescent and emergent adult growth cognition and development as it relates to health care transition preparation
Explain appropriate comparison of donors to matched controls
Discuss research techniques that can be used to gain information on long-term risks, and their strengths and limitations
Describe the early results of the ALTOLD study
Discuss the goals and design of the ReLIVE trial (long-term follow-up of kidney donors)
Discuss how successful pancreas transplants restore normal glucose hemostasis and prevent, halt, or reverse the development or progression of secondary complications of diabetes
List the three categories in which Pancreas transplants are performed
Discuss the eligibility criteria for islet transplantation
Discuss the current research objectives in the field of islet transplantation
Cite the immunological challenges posed by composite tissue transplantation
Discuss the results and long term problems of immunosuppression in VCA
Discuss social/psychological factors relevant in the timing of hand transplantation
Define the role of the initial injury in VCA options
Define sarcopenia and how it’s measured
Explain the implications of sarcopenia on surgical outcomes
Compare frailty and other measures of risk
Quantify associations between frailty and transplant outcomes
Summarize key findings of exercise intervention trials in transplantation
Discuss the current status of living donor follow-up in the USA
Relay the current status of living donor complications in the USA
Identify burden that accompanies living donor follow up for transplant centers
Describe alternative pathways to ensure an adequate knowledge base and living donor safety
Quantify associations between frailty and transplant outcomes
Review the ethical foundations of living donor transplants
Examine risk/benefit assessments as they relate to the donor-recipient dyad
Discuss the ethical principles involved in organ allocation and the concept of double equipoise
Explain the components of informed consent for living organ donors
Identify steps to take for evaluation of possible encephalitis in donors
Discuss the importance of timely communication if donor encephalitis identified after transplantation
Identify factors that predict progression of HCC
Identify suitable candidates for bridge therapy for HCC
Discuss the goals and expectation of tumor down-staging
List the current challenges in VCA including the need to alter risk-benefit balance for widespread clinical application
Identify the next steps toward implementation of VCA
Describe the current state of facial reconstruction
Define the role and indications for facial transplantation
List some causes of late graft loss
Discuss techniques of a multi organ transplant procedure
Discuss mucosal homeostasis and review human studies of immune function in intestine transplantation; relate both to success and failure after intestine transplant
Review and evaluate the latest advances in xenotransplantation science
Discuss the problem of coagulation dysregulation in experimental solid organ xenotransplantation
Discuss new developments in the genetic modification of donor pigs to address this issue
Define the role of B cell depletion in xenograft survival
Describe the role of co stimulation blockade in suppressing xenogeneic response
Discuss the progress in transplantation immunology, pancreatic and isolated islet transplantation
Recognize limitations of current immunosuppressive regimens
Discuss various approaches to tolerance induction
Discuss management of acute liver failure, cell encapsulation, and cell transplantation
Discuss xenotransplantation of neural cells in a pig-to-primate model
Discuss the immunological barrier in xenoislet transplantation
Compare the mechanisms of immunological rejection between pig-to-rodent and pig-to-NHP xenoislet transplantation setting
Describe the genetic theory of infectious diseases
Cite the known genetic etiologies of pediatric tuberculosis, herpes simplex encephalitis, and invasive pneumococcal diseases
Describe the role of the endothelial cell in CAV Endothelial associated Biomarkers of CAV
Describe the role of VEGF in CAV pathogenesis
Identify and determine the prognosis of cardiac allograft vasculopathy as well as the clinical characteristics of this disease
Discuss therapeutic approaches currently used to ameliorate and prevent cardiac allograft vasculopathy as well as new approaches and therapies being developed to more effectively treat and prevent this disease
Explain the molecular and cellular basis of the pathophysiology of cardiac allograft vasculopathy
Describe how bone marrow niches affect; hematopoietic stem cell collection, hematopoietic stem cell engraftment, and residual disase in the setting of bone marrow transplantation for hematologic malignancies
Discuss the mechanisms and methods for acheiving tolerance in transplantation
Discuss phenotype and mechanism of action of murine and human facilitating cells
Explain how to induce stable mixed chimerism and how it results in organ transplant tolerance
Define the role of microbiota in intestinal graft-versus-host-disease (GvHD)
Describe changes in prevalence of multi-drug-resistant bacteria causing infections in children undergoing SOT
Discuss the importance of antimicrobial stewardship & infection prevention in decreasing the emergence and spread of multi-drug resistant bacteria
Discuss the impact of the underlying disease (renal, hepatic or cardiac) on bone health prior to transplantation in children and adolescents
Discuss the skeletal effects of glucocorticoids and other immunosuppressants in children and adolescents
Identify the major causes of the obesity epidemic in the United States
Describe how the comorbidities of obesity lead to the need for solid organ
Describe current trends in clinical practice for coordinators and NP/PA's
Discuss the prevalence of alcohol consumption after transplantation and its impact on outcomes
Compare and contrast the pipeline immunosuppressive agents and understand their potential place in management of transplant recipients
Identify non-pharmacologic and pharmacologic therapy in management of hypertension
Discuss surveillance necessary for commonly associated opportunitic infections
Define chimerism and identify different
Discuss mechanism of chimerism in tolerance
Discuss the need for tolerance
Describe mixed chimerism as an approach to tolerance
Discuss pathology and processes in advanced phases of liver transplantation
Identify 3 or 4 diagnostic entities that present difficulties, mostly from the point of view of clinicopathological integration
Discuss thrombotic microangiopathy, late occurring FSGS, and transplant glomerulopathy with negative DSA
Discuss how Rapamycin acts by inhibition of at least two distinct multi-protein complexes containing the enzyme mTOR
Discuss the role of Notch ligands and receptors in graft-versus-host disease
Discuss the immune and viral factors contributing to development of PTLD
Objective 1: Provide a forum for exchange of new scientific and clinical information relevant to solid organ and tissue transplantation
By meeting the above objective my professional competence will increase because I have acquired new strategies to use in my practice.
By meeting the above objective my professional performance will improve because I should be able to implement the new strategies.
By meeting the above objective my patient outcomes should improve due to the implementation of newly-learned strategies.
Objective 2: Create an arena for the interchange of ideas regarding care and management of organ and tissue transplant recipients
By meeting the above objective my professional competence will increase because I have acquired new strategies to use in my practice.
By meeting the above objective my professional performance will improve because I should be able to implement the new strategies.
By meeting the above objective my patient outcomes should improve due to the implementation of newly-learned strategies.
Objective 3: Facilitate discussions of the socioeconomic, ethical and regulatory issues related to solid organ and tissue transplantation
By meeting the above objective my professional competence will increase because I have acquired new strategies to use in my practice.
By meeting the above objective my professional performance will improve because I should be able to implement the new strategies.
By meeting the above objective my patient outcomes should improve due to the implementation of newly-learned strategies.
Please answer the following:
Do you believe this activity was appropriate for the scope of your professional activities?
Was the educational content scientifically sound?
If faculty spoke about off-label or investigational uses of a product, was that information disclosed to you?
Was the mode of education effective to learning?
If you answered "No" to any of the above questions, please explain.
Did you perceive any product/service/company/commercial bias in any educational session you attended or materials you received?
If you answered "Yes" to the above question, please detail the situation below (e.g. session title, speaker name):
Were you solicited by sales personnel in an educational room (other areas do not matter) while you attended this educational activity?
If you answered "Yes" to the above question, please explain in detail (e.g. who, when, where):
How much did you learn as a result of this education program?
What specifically did you learn during this activity that you intend to integrate into your practice?

What questions have arisen in your practice for which you need answers/strategies that you can implement?

What patient/client problems or patient/client challenges do you feel you are not able to address appropriately or to your satisfaction?
What problems are your patients/clients communicating to you that need attention or follow up?

Are you interested in basic, intermediate or advanced level trainings?

What barriers might you have that would interfere with implementation of new information learned from this training?

How can this training (the overall meeting) be improved to better impact competence, performance and/or patient/client outcomes?

Additional comments:

Mr question